Source: Chapter 26 from Skorecki, K et al. 2016
Using these urine albumin to creatinine ratios to approximate protein excretion per 24 hours requires the assumption that daily creatinine excretion is 1.0 grams / 24 hours
What severity of proteinuria did our patient have?
Urine Albumin: 400.0 mg/dL
uACR = 4,395 mg/g
Urine Protein: >600.0 mg/dL
uPCR = >6,593 mg/g
Nephrotic Range
Does our patient have nephrotic syndrome?
Maybe. Does have nephrotic range proteinuria and peripheral edema, though minimal hypoalbuminemia (3.3 g/dL)
Source: Kelepouris, E. and Rovin, B. 2021
Criteria
Nephrotic Range Proteinuria (> 3.5 g / 24 hrs)
Hypoalbuminemia (< 3 - 3.5 g/dL)
Peripheral Edema
Additional Complications
Hyperlipidemia
Hypercoaguability
Risk of infection
Source: Chapter 32 from Skorecki, K et al. 2016